it's not a known issue with the IU - confirmed last night.
Most likely, it was a user and/or SQL issue during the update. It makes schema
changes in the DB, and possible custom code or some other anomaly caused the
issue.
Of course, it might be a 100 other things as well. Assuming you thoroughly
documented the process, I would go back and see every change made (web app,
servers, topology, etc). Did you take the farm offline to do the IU?