Sure, the user management permissions are separated from the other
permissions. For WSS check out:
Manage site Groups - Create, change, and delete site groups, including
adding users to the site groups and specifying which rights are assigned
to a site group.
Manage List Permissions - Grant, deny, or change user permissions to a
list.
Create Cross-Site Groups - Create a group of users that can be granted
access to any site within the site collection.
For Portal:
Manage Area Permissions - Add, remove, or change user rights for an area
You can play with those until you get the rights you desire for your
power users.